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Writer's pictureChristine Silguero

The Different Types of Magnesium

Updated: Jul 2


Magnesium is a vital mineral involved in over 300 biochemical reactions in the body, playing a key role in muscle function, nerve transmission, and energy production. It's also crucial for immune health, making it particularly important for those managing autoimmune diseases. In this article, we'll explore the different types of magnesium, their specific benefits, and how they can aid in the management of autoimmune diseases.



Understanding Magnesium

Magnesium is available in several forms, each with unique properties and benefits. Here’s a breakdown of the most common types of magnesium and their specific uses:

  1. Magnesium Citrate

  2. Magnesium Glycinate

  3. Magnesium Malate

  4. Magnesium Threonate

  5. Magnesium Oxide

  6. Magnesium Chloride

  7. Magnesium Sulfate

  8. Magnesium L-Threonate



Benefits of Different Types of Magnesium


Magnesium Citrate

  • Benefits: Magnesium citrate is highly bioavailable, meaning it is easily absorbed by the body. It is commonly used to alleviate constipation and improve digestive health.

  • Autoimmune Support: For those with autoimmune diseases that affect the digestive system, such as Crohn's disease or ulcerative colitis, magnesium citrate can help maintain regular bowel movements and reduce discomfort.



Magnesium Glycinate

  • Benefits: Known for its calming effects, magnesium glycinate is often used to reduce anxiety, promote relaxation, and improve sleep quality.

  • Autoimmune Support: Good sleep and reduced stress are essential for managing autoimmune diseases. Magnesium glycinate can help improve sleep patterns and reduce stress-related flare-ups.


Magnesium Malate

  • Benefits: Magnesium malate is known for its ability to support energy production and alleviate muscle pain.

  • Autoimmune Support: For individuals with autoimmune conditions like fibromyalgia, which is characterized by chronic pain and fatigue, magnesium malate can help reduce pain and improve energy levels.


Magnesium Threonate

  • Benefits: This form of magnesium is renowned for its ability to cross the blood-brain barrier, making it effective for cognitive health and memory enhancement.

  • Autoimmune Support: Cognitive dysfunction and brain fog are common in autoimmune diseases such as lupus and multiple sclerosis. Magnesium threonate can support brain health and improve cognitive function.



Magnesium Oxide

  • Benefits: Magnesium oxide is often used as a supplement for magnesium deficiency and as a relief for heartburn and indigestion.

  • Autoimmune Support: While not as bioavailable as other forms, magnesium oxide can help maintain adequate magnesium levels, which is essential for overall immune health.


Magnesium Chloride

  • Benefits: This form of magnesium is highly absorbable and can be used topically (as a lotion or oil) or orally to support muscle and joint health.

  • Autoimmune Support: Topical application can be particularly beneficial for individuals with autoimmune conditions like rheumatoid arthritis, providing localized relief from pain and inflammation.


Magnesium Sulfate

  • Benefits: Commonly known as Epsom salt, magnesium sulfate is often used in baths to soothe sore muscles and reduce inflammation.

  • Autoimmune Support: Epsom salt baths can provide relief from joint pain and muscle stiffness associated with autoimmune diseases, promoting relaxation and reducing inflammation.


Magnesium L-Threonate

  • Benefits: This newer form of magnesium is designed for its potential cognitive benefits and ability to support brain health.

  • Autoimmune Support: By supporting brain health and cognitive function, magnesium L-threonate can be beneficial for those experiencing brain fog and cognitive issues related to autoimmune diseases.


How Magnesium Helps with Autoimmune Diseases

Autoimmune diseases occur when the immune system mistakenly attacks the body’s own tissues, leading to chronic inflammation and a range of symptoms depending on the specific condition. Magnesium can play a supportive role in managing these diseases through various mechanisms:

  1. Reducing Inflammation: Magnesium has anti-inflammatory properties that can help lower the levels of inflammatory markers in the body, potentially reducing the severity of autoimmune flare-ups.

  2. Supporting Immune Function: Adequate magnesium levels are essential for proper immune function. It helps regulate immune responses and can prevent the overactivation of the immune system that leads to autoimmunity.

  3. Improving Sleep and Reducing Stress: Magnesium’s role in promoting relaxation and better sleep can be crucial for those with autoimmune diseases, as poor sleep and high stress can exacerbate symptoms.

  4. Enhancing Energy Levels: Chronic fatigue is a common issue in many autoimmune diseases. Magnesium supports energy production at the cellular level, helping to combat fatigue and improve overall energy levels.

  5. Alleviating Muscle and Joint Pain: Many autoimmune conditions, such as rheumatoid arthritis and lupus, involve muscle and joint pain. Magnesium can help relax muscles and reduce pain, improving quality of life.


Magnesium is a versatile and essential mineral with numerous health benefits, particularly for those managing autoimmune diseases. By understanding the different types of magnesium and their specific uses, individuals can better tailor their supplementation to meet their unique health needs. Whether it’s reducing inflammation, supporting immune function, or improving sleep, magnesium can play a vital role in enhancing overall health and managing autoimmune conditions.


Hope this helps <3

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